Gene Expression

Datasets Available to Download ( alphabetical order by first author )

Liver expression of B6.C3H-6T (6T) (congenic mice with low serum IGF-1) and C57BL/6J mice

PPARG by dietary fat interaction influences bone mass in mice and humans
Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ.
J Bone Miner Res. 2008 Sep;23(9):1398-408. PMCID: PMC2683155 [ PDF ]

Femurs of C57BL/6J and C3H/HeJ mice on low fat diet or low fat with Rosiglitazone diet [ login ]

Ackert-Bicknell CL, Shockley KR, Horton LG, Lecka-Czernik B, Churchill GA, Rosen CJ.
Strain-specific effects of rosiglitazone on bone mass, body composition, and serum insulin-like growth factor-I
Endocrinology. 2009 Mar;150(3):1330-40.

PPARgamma2 gene expression signature in U-33 / gamma2 and U-33/c mouse cell lines

Lecka-Czernik B, Ackert-Bicknell C, Adamo ML, Marmolejos V, Churchill GA, Shockley KR, Reid IR, Grey A, Rosen CJ.
Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo
Endocrinology. 2007 Feb;148(2):903-11.PMCID: PMC1851001 [ PDF ]

Shockley KR, Lazarenko OP, Czernik PJ, Rosen CJ, Churchill GA, Lecka-Czernik B.
PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells
J Cell Biochem. 2009 Feb 1;106(2):232-46. PMCID: PMC2745312 [ PDF ]

Shockley KR, Rosen CJ, Churchill GA, Lecka-Czernik B.
PPARgamma2 Regulates a Molecular Signature of Marrow Mesenchymal Stem Cells
PPAR Res. 2007;2007:81219. PMCID: PMC2234088 [ PDF ]

Temporal gene expression differences in mouse brain during sleep

Mackiewicz M, Shockley KR, Romer MA, Galante RJ, Zimmerman JE, Naidoo N, Baldwin DA, Jensen ST, Churchill GA, Pack AI.
Macromolecule biosynthesis: a key function of sleep
Physiol Genomics. 2007 Nov 14;31(3):441-57. [ PDF ]

Gene expression response to diet in a strain survey

Shockley KR, Witmer D, Burgess-Herbert SL, Paigen B, Churchill GA.
The Effects of Atherogenic Diet on Hepatic Gene Expression Across Mouse Strains
Physiol Genomics. 2009 Aug 11.

Affymetrix expression data used to estimate p-values in small microarray experiments

Yang H, Churchill G.
Estimating p-values in small microarray experiments
Bioinformatics. 2007 Jan 1;23(1):38-43.

BxA intercross expression and genotype data [ login ]

Unpublished. Researchers involved:
Yang H, Tsaih S, Li R, Stylianou I, DiPetrillo K, Paigen B, Churchill GA