Mouse Diversity Genotyping Array
The Mouse Diversity Genotyping Array is the most advanced high-density mouse genotyping microarray available. It was designed by Center investigators Drs. Fernando Pardo-Manuel de Villena and Gary Churchill. This single, custom Affymetrix array can simultaneously assay over 600,000 single nucleotide polymorphisms (SNPs) and over 900,000 invariant genomic probes (IGPs) in a mouse DNA sample.
A customized and versatile high-density genotyping array for the mouse
Yang H, Ding Y, Hutchins LN, Szatkiewicz J, Bell TA, Paigen BJ, Graber JH, de Villena FP, Churchill GA.
Nat Methods. 2009 Aug 9.
High-density array: how it was done
Find out how it was constructed, and how it can accelerate your research.
New Array Can Give Detailed Genetic Profile of Any Mouse
JAX® NOTES Issue 515, Fall 2009
Watch an interview of Professor Churchill answering the following questions:
- How did you choose the array’s SNPs? (4:08)
- How did you ensure the array’s reliability? (2:07)
- How are IGPs different from SNPs, and how will they increase the array’s utility? (4:23)
- What are some of the quality control measures you used to validate the array? (3:28)
- What will be some to the most important uses of the array? (2:41)
- How will the array help researchers identify genes associated with disease? (3:35)
The Jackson Laboratory now offers a JAX Mouse Diversity Genotyping Array Service utilizing this innovative genotyping microarray.
Probe Annotation files (Version 2.0, Mouse Build 37)
SNP annotation file
IGP annotation file
Strains and Genotypes in the Training Set [ Strain Names ]
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